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1

Synthesis and Reactivity of Propargylamines in Organic Chemistry

Lauder, Kate, Toscani, Anita, Scalacci, Nicolò, Castagnolo, Daniele

Journal:

Chemical Reviews

Année:

2017

Langue:

english

Fichier:

PDF, 9.41 MB

english, 2017

2

Toward the Synthesis of the Antibiotic Branimycin: Novel Approaches to Highly Substituted cis-Decalin Systems

Johann Mulzer, Daniele Castagnolo, Wolfgang Felzmann, Stefan Marchart, Christian Pilger, Valentin S. Enev

Journal:

Chemistry - A European Journal

Année:

2006

Langue:

english

Fichier:

PDF, 509 KB

english, 2006

3

Enantioselective Synthesis of 1-Aryl-2-propenylamines: A New Approach to a Stereoselective Synthesis of the Taxol® Side Chain.

Daniele Castagnolo, Silvia Armaroli, Federico Corelli, Maurizio Botta

Journal:

Année:

2004

Fichier:

PDF, 137 KB

2004

4

ChemInform Abstract: One-Pot Multicomponent Synthesis of 2,3-Dihydropyrans: New Access to Furanose—Pyranose 1,3-C-C-Linked-Disaccharides.

Daniele Castagnolo, Lorenzo Botta, Maurizio Botta

Journal:

Année:

2009

Fichier:

PDF, 35 KB

2009

5

ChemInform Abstract: Alkyne-Enol Ether Cross-Metathesis in the Presence of CuSO4: Direct Formation of 3-Substituted Crotonaldehydes in Aqueous Medium.

Daniele Castagnolo, Lorenzo Botta, Maurizio Botta

Journal:

Année:

2009

Fichier:

PDF, 23 KB

2009

6

ChemInform Abstract: Synthesis and Biological Evaluation of New Enantiomerically Pure Azole Derivatives as Inhibitors of Mycobacterium tuberculosis.

Daniele Castagnolo, Marco Radi, Filippo Dessi, Fabrizio Manetti, Manuela Saddi, Rita Meleddu, Alessandro De Logu, Maurizio Botta

Journal:

Année:

2009

Fichier:

PDF, 24 KB

2009

7

ChemInform Abstract: Domino Alkylation—Cyclization Reaction of Propargyl Bromides with Thioureas/Thiopyrimidinones: A New Facile Synthesis of 2-Aminothiazoles and 5H-Thiazolo[3,2-a]pyrimidin-5-ones.

Daniele Castagnolo, Mafalda Pagano, Martina Bernardini, Maurizio Botta

Journal:

Année:

2009

Fichier:

PDF, 32 KB

2009

8

ChemInform Abstract: Microwave-Assisted Organocatalytic Multicomponent Knoevenagel/Hetero Diels—Alder Reaction for the Synthesis of 2,3-Dihydropyran[2,3-c]pyrazoles.

Marco Radi, Vincenzo Bernardo, Beatrice Bechi, Daniele Castagnolo, Mafalda Pagano, Maurizio Botta

Journal:

Année:

2010

Fichier:

PDF, 27 KB

2010

9

ChemInform Abstract: Iron-Catalyzed Cross-Coupling Between 1-Bromoalkynes and Grignard-Derived Organocuprate Reagents.

Daniele Castagnolo, Maurizio Botta

Journal:

Année:

2010

Fichier:

PDF, 25 KB

2010

10

ChemInform Abstract: Guanylated Diamines, Triamines, and Polyamines: Chemistry and Biological Properties

Daniele Castagnolo, Silvia Schenone, Maurizio Botta

Journal:

Année:

2011

Fichier:

PDF, 18 KB

2011

11

Ligand-Based Virtual Screening, Parallel Solution-Phase and Microwave-Assisted Synthesis as Tools to Identify and Synthesize New Inhibitors of Mycobacterium tuberculosis

Fabrizio Manetti, Matteo Magnani, Daniele Castagnolo, Laura Passalacqua, Maurizio Botta, Federico Corelli, Manuela Saddi, Delia Deidda, Alessandro De Logu

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 564 KB

english, 2006

12

Practical Syntheses of Enantiomerically Pure N-Acetylbenzhydrylamines

Daniele Castagnolo, Gianluca Giorgi, Raffaella Spinosa, Federico Corelli, Maurizio Botta

Journal:

European Journal of Organic Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 211 KB

english, 2007

13

Macrocyclization of Di-Boc-guanidino-alkylamines Related to Guazatine Components: Discovery and Synthesis of Innovative Macrocyclic Amidinoureas

Daniele Castagnolo, Francesco Raffi, Gianluca Giorgi, Maurizio Botta

Journal:

European Journal of Organic Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 201 KB

english, 2009

14

Iron-Catalyzed Cross-Coupling between 1-Bromoalkynes and Grignard-Derived Organocuprate Reagents

Daniele Castagnolo, Maurizio Botta

Journal:

European Journal of Organic Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 211 KB

english, 2010

15

Iron-Catalyzed Cross-Coupling between 1-Bromoalkynes and Grignard-Derived Organocuprate Reagents

Daniele Castagnolo, Maurizio Botta

Journal:

European Journal of Organic Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 133 KB

english, 2010

16

Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J

Maurizio Botta, Silvia Armaroli, Daniele Castagnolo, Gabriele Fontana, Paula Pera, Ezio Bombardelli

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 171 KB

english, 2007

17

Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis

Daniele Castagnolo, Alessandro De Logu, Marco Radi, Beatrice Bechi, Fabrizio Manetti, Matteo Magnani, Sibilla Supino, Rita Meleddu, Lorenza Chisu, Maurizio Botta

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 414 KB

english, 2008

18

Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis

Daniele Castagnolo, Marco Radi, Filippo Dessì, Fabrizio Manetti, Manuela Saddi, Rita Meleddu, Alessandro De Logu, Maurizio Botta

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 198 KB

english, 2009

19

Stereoselective protecting group free synthesis of d,l-gulose ethyl glycoside via multicomponent enyne cross metathesis—hetero Diels–Alder reaction

Daniele Castagnolo, Lorenzo Botta, Maurizio Botta

Journal:

Carbohydrate Research

Année:

2009

Langue:

english

Fichier:

PDF, 243 KB

english, 2009

20

Studies towards the synthesis of the bicyclic 3,8-secotaxane diterpenoid system using a ring closing metathesis strategy

Michela L. Renzulli, Luc Rocheblave, Stanislava I. Avramova, Elena Galletti, Daniele Castagnolo, Andrea Tafi, Federico Corelli, Maurizio Botta

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 553 KB

english, 2007

21

Enantioselective synthesis of 1-aryl-2-propenylamines: a new approach to a stereoselective synthesis of the Taxol® side chain

Daniele Castagnolo, Silvia Armaroli, Federico Corelli, Maurizio Botta

Journal:

Tetrahedron: Asymmetry

Année:

2004

Langue:

english

Fichier:

PDF, 340 KB

english, 2004

22

Microwave-assisted ethylene–alkyne cross-metathesis: synthesis of chiral 2-(N-1-acetyl-1-arylmethyl)-1,3-butadienes

Daniele Castagnolo, Michela L. Renzulli, Elena Galletti, Federico Corelli, Maurizio Botta

Journal:

Tetrahedron: Asymmetry

Année:

2005

Langue:

english

Fichier:

PDF, 121 KB

english, 2005

23

Synthesis of enantiomerically pure α-[4-(1-substituted)-1,2,3-triazol-4-yl]-benzylacetamides via microwave-assisted click chemistry: towards new potential antimicrobial agents

Daniele Castagnolo, Filippo Dessì, Marco Radi, Maurizio Botta

Journal:

Tetrahedron: Asymmetry

Année:

2007

Langue:

english

Fichier:

PDF, 179 KB

english, 2007

24

One-pot multicomponent synthesis of 2,3-dihydropyrans: new access to furanose–pyranose 1,3-C–C-linked-disaccharides

Daniele Castagnolo, Lorenzo Botta, Maurizio Botta

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 437 KB

english, 2009

25

Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles

Marco Radi, Vincenzo Bernardo, Beatrice Bechi, Daniele Castagnolo, Mafalda Pagano, Maurizio Botta

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 272 KB

english, 2009

26

Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: Part 2. Synthesis of rigid pyrazolones

Daniele Castagnolo, Fabrizio Manetti, Marco Radi, Beatrice Bechi, Mafalda Pagano, Alessandro De Logu, Rita Meleddu, Manuela Saddi, Maurizio Botta

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 385 KB

english, 2009

27

Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors

Dr. Marco Radi, Dr. Mafalda Pagano, Dr. Luigi Franchi, Dr. Daniele Castagnolo, Prof. Silvia Schenone, Dr. Gianni Casaluce, Dr. Claudio Zamperini, Dr. Elena Dreassi, Dr. Giovanni Maga, Dr. Alberta Samu

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 380 KB

english, 2012

28

Antioxidant properties of propargylamine derivatives: assessment of their ability to scavenge peroxynitrite

Stefania Dragoni, Valentina Porcari, Massimo Valoti, Massimo Travagli, Daniele Castagnolo

Journal:

Journal of Pharmacy and Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 140 KB

english, 2006

29

Guanylated Diamines, Triamines, and Polyamines: Chemistry and Biological Properties

Castagnolo, Daniele, Schenone, Silvia, Botta, Maurizio

Journal:

Chemical Reviews

Année:

2011

Langue:

english

Fichier:

PDF, 3.18 MB

english, 2011

30

A Versatile Route to C-6 Arylmethyl-Functionalized S-DABO and Related Analogues

Radi, Marco, Contemori, Lorenzo, Castagnolo, Daniele, Spinosa, Raffaella, Esté, José A., Massa, Silvio, Botta, Maurizio

Journal:

Organic Letters

Année:

2007

Langue:

english

Fichier:

PDF, 100 KB

english, 2007

31

Studies on the acylation of 4-(2-aminoethylthio)-7-nitrobenzofurazan: the role of bases in promoting the formation of fluorescent S-acyl derivatives through S–N Smiles rearrangement

Daniele Castagnolo, Mafalda Pagano, Martina Bernardini, Maurizio Botta

Journal:

Tetrahedron Letters

Année:

2012

Langue:

english

Fichier:

PDF, 321 KB

english, 2012

32

Crotylation versus Propargylation: Two Routes for the Synthesis of the C13−C18 Fragment of the Antibiotic Branimycin

Felzmann, Wolfgang, Castagnolo, Daniele, Rosenbeiger, Daniela, Mulzer, Johann

Journal:

Journal of Organic Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 142 KB

english, 2007

33

Carbolithiation of S -Alkenyl- N -aryl Thiocarbamates: Carbanion Arylation in a Connective Route to Tertiary Thiols

Castagnolo, Daniele, Foley, Daniel J., Berber, Hatice, Luisi, Renzo, Clayden, Jonathan

Journal:

Organic Letters

Année:

2013

Langue:

english

Fichier:

PDF, 809 KB

english, 2013

34

Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species

Sanguinetti, Maurizio, Sanfilippo, Stefania, Castagnolo, Daniele, Sanglard, Dominique, Posteraro, Brunella, Donzellini, Giovanni, Botta, Maurizio

Journal:

ACS Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 462 KB

english, 2013

35

Discovery and synthesis of novel benzofurazan derivatives as inhibitors of influenza A virus

Kessler, Ulrich, Castagnolo, Daniele, Pagano, Mafalda, Deodato, Davide, Bernardini, Martina, Pilger, Beatrice, Ranadheera, Charlene, Botta, Maurizio

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 608 KB

english, 2013

36

Intramolecular arylation of amino acid enolates

Atkinson, Rachel C., Leonard, Daniel J., Maury, Julien, Castagnolo, Daniele, Volz, Nicole, Clayden, Jonathan

Journal:

Chemical Communications

Année:

2013

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2013

37

Synthesis of New Linear Guanidines and Macrocyclic Amidinourea Derivatives Endowed with High Antifungal Activity against Candida spp. and Aspergillus spp. †

Manetti, Fabrizio, Castagnolo, Daniele, Raffi, Francesco, Zizzari, Alessandra T., Rajamäki, Suvi, D’Arezzo, Silvia, Visca, Paolo, Cona, Alessandra, Fracasso, Maria Enrica, Doria, Denise, Posteraro, B

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 795 KB

english, 2009

38

The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors

Pagano, Mafalda, Castagnolo, Daniele, Bernardini, Martina, Fallacara, Anna Lucia, Laurenzana, Ilaria, Deodato, Davide, Kessler, Ulrich, Pilger, Beatrice, Stergiou, Lilli, Strunze, Stephan, Tintori, Cr

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 829 KB

english, 2014

39

Direct Kinetic Formation of Nonanomeric [6.5]-Spiroketals in Aqueous Media

Castagnolo, Daniele, Breuer, Irene, Pihko, Petri M.

Journal:

Journal of Organic Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 139 KB

english, 2007

40

From Taxuspine X to Structurally Simplified Taxanes with Remarkable P-Glycoprotein Inhibitory Activity

Castagnolo, Daniele, Contemori, Lorenzo, Maccari, Giorgio, Avramova, Stanislava I., Neri, Annalisa, Sgaragli, Gianpietro, Botta, Maurizio

Journal:

ACS Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2010

41

Enantioselective carbolithiation of S-alkenyl-N-aryl thiocarbamates: kinetic and thermodynamic control

Castagnolo, Daniele, Degennaro, Leonardo, Luisi, Renzo, Clayden, Jonathan

Journal:

Organic & Biomolecular Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.76 MB

english, 2015

42

Synthesis of 1,2,3-Substituted Pyrroles from Propargylamines via a One-Pot Tandem Enyne Cross Metathesis–Cyclization Reaction

Chachignon, Helene, Scalacci, Nicolò, Petricci, Elena, Castagnolo, Daniele

Journal:

Journal of Organic Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 518 KB

english, 2015

43

Domino Alkylation-Cyclization Reaction of Propargyl Bromides with Thioureas/Thiopyrimidinones: A New Facile Synthesis of 2-Aminothiazoles and 5H-Thiazolo[3,2-a]pyrimidin-5-ones

Castagnolo, Daniele, Pagano, Mafalda, Bernardini, Martina, Botta, Maurizio

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 95 KB

english, 2009

44

Rethinking the old antiviral drug moroxydine: discovery of novel analogues as anti-hepatitis C virus (HCV) agents

Magri, Andrea, Reilly, Roisin, Scalacci, Nicolò, Radi, Marco, Hunter, Michael, Ripoll, Manon, Patel, Arvind H., Castagnolo, Daniele

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 846 KB

english, 2015

45

A multicomponent pharmacophore fragment-decoration approach to identify selective LRRK2-targeting probes

Tassini, Sabrina, Castagnolo, Daniele, Scalacci, Nicolò, Kissova, Miroslava, Armijos-Rivera, Jorge I., Giagnorio, Federica, Maga, Giovanni, Costantino, Gabriele, Crespan, Emmanuele, Radi, Marco

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2016

46

Alkyne-Enol Ether Cross-Metathesis in the Presence of CuSO 4 : Direct Formation of 3-Substituted Crotonaldehydes in Aqueous Medium

Castagnolo, Daniele, Botta, Lorenzo, Botta, Maurizio

Journal:

Journal of Organic Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 144 KB

english, 2009

47

A microwave-assisted multicomponent protocol for the synthesis of benzofuran-2-carboxamides

Vincetti, Paolo, Brianza, Anna, Scalacci, Nicolò, Costantino, Gabriele, Castagnolo, Daniele, Radi, Marco

Journal:

Tetrahedron Letters

Année:

2016

Langue:

english

Fichier:

PDF, 781 KB

english, 2016

48

Microwave-Assisted Domino Reactions of Propargylamines with Isothiocyanates: Selective Synthesis of 2-Aminothiazoles and 2-Amino-4-methylenethiazolines

Scalacci, Nicoló, Pelloja, Chiara, Radi, Marco, Castagnolo, Daniele

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 175 KB

english, 2016

49

ChemInform Abstract: Carbolithiation of S-Alkenyl-N-aryl thiocarbamates: Carbanion Arylation in a Connective Route to Tertiary Thiols.

Castagnolo, Daniele, Foley, Daniel J., Berber, Hatice, Luisi, Renzo, Clayden, Jonathan

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 39 KB

english, 2013

50

ChemInform Abstract: Synthesis of 1,2,3-Substituted Pyrroles from Propargylamines via a One-Pot Tandem Enyne Cross Metathesis-Cyclization Reaction.

Chachignon, Helene, Scalacci, Nicolo, Petricci, Elena, Castagnolo, Daniele

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 30 KB

english, 2015